Susan Hockfield on Studying Electron Microscopy
  Susan Hockfield     Biography    
Recorded: 19 Jan 2024

While I was in this pain workshop on the side, remember I'm an electron microscopist, I said, we can solve part of this problem if we know exactly what's being identified by an antibody in a cell. So, I did this electron microscopy study just on the side of this workshop to understand whether the antibodies, each different antibody was differentiated, how it was differentiating cells. And again, oh my goodness, I thought that all of the antibodies would recognize the cell surface, but a different cell surface protein and touch cells versus pain cells, forget about it. So much more complicated. Some of the antibodies recognize the surface of cells, some recognized intracellular organelles that we couldn't quite identify. They were all over the place. I mean, another wonderful puzzle. And so I was, I was totally hooked. And as the summer was, my workshop period, was drawing to an end Birgit said, asked me if I would be interested in pursuing the possibility of joining the lab. And I said, well, I guess so I'm going to Washington to see my friends from graduate school. She said, well, you'd have to meet with Jim. I said – Jim Watson – I said, okay, sure, give me a call. So, I got in my car, drove to Washington. No sooner had I arrived, that Birgit said, Jim would like to see you like the day after tomorrow. So, I said, okay. So, I got in my car and drove back from Washington out to Cold Spring Harbor and met Jim Watson.

Susan Hockfield is a neuroscientist whose research focuses on brain development and glioma, pioneering the use of monoclonal antibody technology demonstrating that early experience results in lasting changes in the molecular structure of the brain. She is a Professor of Neuroscience and President Emerita at MIT. She was the first woman and life scientist to serve as MIT’s sixteenth president from 2004-2012.

Hockfield earned her B.A. in biology from the University of Rochester (1973) and a Ph.D. from Georgetown University at the School of Medicine (1979). In 1980, Hockfield completed an NIH postdoctoral fellowship at the University of California at San Francisco. She then joined the scientific staff at the Cold Spring Harbor Laboratory, New York where she ran her own lab for five years. She also served as director of the Summer Neurobiology Program from 1985 to 1997. In 1985, Hockfield became the William Edward Gilbert Professor of Neurobiology at Yale University. She went on to serve as the Dean of the Graduate School of Arts and Sciences from 1998-2002, and Provost from 2003-2004.

In December 2004, Hockfield assumed office as the president of the Massachusetts Institute of Technology. She held this role until June 2012 and continues to hold a faculty appointment as professor of neuroscience and as a member of the Koch Institute for Integrative Cancer Research.

Hockfield has received numerous awards including the Charles Judson Herrick Award from the American Association of Anatomists, the Wilbur Lucius Cross Award from the Yale University Graduate School, the Meliora Citation from the University of Rochester, the Amelia Earhart Award from the Women’s Union, and the Yale Science and Engineering Association 2021 Award for Distinguished Service to Industry, Commerce or Education.

She also holds honorary degrees from Brown University, Duke University, Georgetown University, Mt. Sinai School of Medicine, New York University, Northeastern University, Tsinghua University (Beijing), Université Pierre et Marie Curie, University of Edinburgh, University of Massachusetts Medical School, University of Rochester, and the Cold Spring Harbor Laboratory School of Biological Sciences.

OTHER TOPICS for
Susan Hockfield
LIFE IN SCIENCE
JAMES D. WATSON
CSHL