Recorded: 04 Jan 2024
I had moved, I had left Einstein and moved to Columbia University School of Medicine in 1986. And it was a big move to leave Einstein. And I was chair of the Department of Microbiology and Immunology there. And only one year after I had moved, Stanford came after me and they said I had to move to Stanford. And I said, well, no, I've just moved to Columbia. And this went on for two years. And every time I said, no, the offer got better. And then ultimately, one day, unannounced, Dave Hogness walked into my office at Columbia holding in one arm a dozen yellow roses and in the other arm the blueprints for the new Beckman Center. And everybody in the halls were staring out of their labs and offices saying, that's Dave Hogness, what is he doing here? And that was really quite pivotal.
Lucy Shapiro (b. 1940, New York City) is a developmental biologist and Professor Emeritus of Developmental Biology at Stanford University where she has been a faculty member since 1989. She held the Virginia and D.K. Ludwig Chair in Cancer Research and served as director of the Beckman Center for Molecular and Genetic Medicine. Dr. Shapiro’s lab has focused on studying Caulobacter crescentus, one of the simplest organisms that divides asymmetrically into different cell types, to uncover fundamental principles of developmental biology.
Dr. Shapiro received her Bachelor of Arts in Biology and Fine Arts from Brooklyn College in 1962, and her Ph.D. In Molecular Biology from Albert Einstein College of Medicine in 1966. In 1986, Shapiro moved to the Columbia University School of Medicine as the first female chair of the Department of Microbiology and Immunology. Two years later, in 1989, Shapiro moved to Stanford University and founded the Department of Developmental Biology.
In the early 1990s, Dr. Shapiro became involved in policy work. She was invited to the White House to speak to President Bill Clinton and his Cabinet about the potential threats to the public posed by the increase in antibiotic resistance, emerging infectious diseases, and the possibility of bioterrorism. She then went on to serve as a scientific advisor to the Clinton administration and advisor on bioterrorism to the secretary of homeland security, Tom Ridge, and to the secretary of state, Condoleezza Rice during the George W. Bush administration.
In addition to her research, Dr. Shapiro co-founded the anti-infectives discovery company Anacor Pharmaceuticals to develop new types of antibiotics and antifungals. This has resulted in the production of two FDA approved drugs; Kerydin, a treatment for toenail fungus and Crisaborole, to treat atopic dermatitis. Anacor Pharmaceuticals was acquired by Pfizer in May 2016. She also co-founded Boragen, an agricultural innovation company that merged with AgriMetis to form 5Metis, Inc, where she serves on the board. She also serves on the board of directors at GlaxoSmithKline and Pacific BioSciences, Inc.
Dr. Shapiro has received numerous awards including the National Medal of Science awarded by President Barack Obama, the Linus Pauling Medal, Dickson Prize in Science, Canada Gairdner International Award, Federation of American Societies for Experimental Biology (FASEB) Excellence in Science Award, the Selman Waksman Award, the Louisa Gross Horwitz Prize, the Abbott Lifetime Achievement Award, the John Scott Award, and the Pearl Meister Greengard Prize.